The principle on which Targeted therapies work is identifying specific molecular/genetic abnormalities in tumor DNA/RNA/Proteins. These molecular targets are involved in the growth and survival of cancer cells, blocking them can kill cancer cells or slow their growth, while keeping damage to healthy cells at a minimum. This is done by genetic analysis of the tumor tissue.
Targeted therapy drugs target these genetic/molecular abnormalities very specifically and control cancer growth and often cause the signs and symptoms of cancer to reduce or even disappear.
Targeted therapies are now available in many cancers but Lung cancer is one condition wherein many Targeted therapies have become standard of treatment and made significant improvement in survival.
Generally, it is a continuous treatment.
The whole idea of Targeted therapy is to minimize harm to healthy cells but it can still have side effects. These will vary for each person depending on which drug you are taking and how your body responds.
Commonly the side effects from targeted therapy can include: